Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18855709 | 0.84 | AR (0.46) | CNR2PANK3MAPTCHEK1KCNH2 | |
| SCHEMBL24242896 | 0.82 | AR (0.49) | CNR2PANK3ALDH1A1MAPTLMNA | |
| SCHEMBL20355455 | 0.79 | PIM1 (0.46) | PANK3ALDH1A1HPGDCYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL20339246 | 0.78 | PIM1 (0.45) | PANK3ALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL23980717 | 0.77 | CNR2 (0.54) | CNR2ALDH1A1HPGDHTTCYP1A2 | |
| SCHEMBL18641203 | 0.76 | PANK3 (0.46) | PANK3CHEK1KCNH2GPR119RIPK1 | |
| SCHEMBL20355456 | 0.76 | PANK3 (0.46) | PANK3ALDH1A1KDM4ECHEK1KCNH2 | |
| SCHEMBL523894 | 0.75 | ADK (0.56) | CNR2PANK3ALDH1A1HPGDHTT | |
| SCHEMBL153260 | 0.75 | CHEK1 (0.52) | CNR2ALDH1A1HPGDHTTCYP1A2 | |
| SCHEMBL12488456 | 0.75 | PANK3 (0.43) | PANK3CHEK1KCNH2GPR119RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112584898-B | P2X 3 Receptor antagonists | 瑞蔻达蒂化学和制药工业股份有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-112584898-A | P2X3Receptor antagonists | 瑞蔻达蒂化学和制药工业股份有限公司 | 2021-03-30 | — | — | CN | disclosed |