Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29046738 | 0.86 | PPARA (0.53) | CYP4A11CYP4F2THRBPPARACA2 | |
| SCHEMBL2843880 | 0.85 | CYP4A11 (0.56) | CYP4A11CYP4F2THRBPPARACA2 | |
| SCHEMBL6745680 | 0.85 | FFAR1 (0.58) | THRBPPARALTA4HEPHX2FFAR1 | |
| SCHEMBL237478 | 0.83 | THRB (0.71) | THRBTHRAPTGS2MEN1ALDH1A1 | |
| SCHEMBL8441319 | 0.82 | KMT2A (0.53) | CYP4A11CYP4F2THRBPPARACA2 | |
| SCHEMBL17473007 | 0.81 | THRB (0.69) | THRBTHRAPTGS2MEN1USP2 | |
| SCHEMBL17473112 | 0.81 | THRB (0.69) | THRBTHRAPTGS2MEN1USP2 | |
| SCHEMBL1834795 | 0.81 | THRB (0.69) | THRBTHRAPTGS2MEN1USP2 | |
| SCHEMBL17473027 | 0.81 | THRB (0.69) | THRBTHRAPTGS2MEN1USP2 | |
| SCHEMBL14938003 | 0.81 | THRB (0.69) | THRBTHRAPTGS2MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3353145-B1 | PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF | XWPHARMA LTD (KY) | 2022-09-28 | — | — | EP | disclosed |
| CN-113061089-A | Prodrugs of gamma-hydroxybutyric acid, compositions and uses thereof | 凯瑞康宁生物工程（武汉）有限公司 | 2021-07-02 | — | — | CN | disclosed |
| CN-108283000-B | Prodrugs of gamma-hydroxybutyric acid, compositions and uses thereof | 凯瑞康宁生物工程（武汉）有限公司 | 2021-04-13 | — | — | CN | disclosed |