Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.50 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.48 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.48 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.48 |
| ▸ | GAPDH | P04406 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | STAT6 | P42226 | 1/20 | 0.48 |
| ▸ | PI4KA | P42356 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.48 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.48 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28552389 | 0.86 | SLC29A1 (0.40) | SLC29A1ADORA2AADORA2BDOT1LADORA3 | |
| SCHEMBL29884287 | 0.83 | ADORA2A (0.44) | SLC29A1ADORA2AADORA2BDOT1LDPP4 | |
| SCHEMBL30324473 | 0.83 | ADORA1 (0.55) | SLC29A1ADORA2AADORA2BDOT1LDPP4 | |
| SCHEMBL30324459 | 0.83 | ADORA3 (0.54) | SLC29A1ADORA2AADORA2BDOT1LDPP4 | |
| SCHEMBL13265481 | 0.77 | SLC29A1 (0.67) | SLC29A1ADORA2AADORA2BDOT1LDPP4 | |
| SCHEMBL6903709 | 0.74 | SLC29A1 (0.70) | SLC29A1ADORA2AADORA2BDOT1LDPP4 | |
| SCHEMBL9142042 | 0.74 | SLC29A1 (0.70) | SLC29A1ADORA2AADORA2BDOT1LDPP4 | |
| SCHEMBL6887353 | 0.74 | SLC29A1 (0.70) | SLC29A1ADORA2AADORA2BDOT1LDPP4 | |
| SCHEMBL4081006 | 0.74 | SLC29A1 (0.70) | SLC29A1ADORA2AADORA2BDOT1LDPP4 | |
| SCHEMBL1979130 | 0.74 | SLC29A1 (0.70) | SLC29A1ADORA2AADORA2BDOT1LDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112714649-A | Novel cyclic dinucleotide derivatives and antibody drug conjugates thereof | 第一三共株式会社 | 2021-04-27 | — | — | CN | disclosed |