SCHEMBL28553501

SCHEMBL28553501

Cc1[nH]c2ccccc2c1C(=O)c1ccc(Cl)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.61
ALDH1A1 P00352 5/20 0.61
MEN1 O00255 4/20 0.61
RAB9A P51151 5/20 0.59
LMNA P02545 5/20 0.59
NPSR1 Q6W5P4 2/20 0.59
MITF O75030 1/20 0.59
POLB P06746 1/20 0.59
NR4A2 P43354 2/20 0.56
MAPT P10636 7/20 0.52
NPC1 O15118 4/20 0.52
MAPK1 P28482 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
HTT P42858 2/20 0.52
PKM P14618 2/20 0.52
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2971584 0.87 MAPT (0.59) KMT2AALDH1A1MEN1RAB9ALMNA
SCHEMBL2355240 0.87 NR4A2 (0.63) KMT2AALDH1A1MEN1RAB9ALMNA
SCHEMBL27854856 0.85 NR4A2 (0.69) KMT2AALDH1A1MEN1RAB9ALMNA
SCHEMBL9691608 0.84 NR4A2 (0.56) KMT2AALDH1A1MEN1RAB9ALMNA
SCHEMBL18180604 0.83 CCNB2 (0.53) KMT2AMEN1LMNAMAPT
SCHEMBL28516701 0.82 MEN1 (0.54) KMT2AALDH1A1MEN1RAB9ALMNA
SCHEMBL9037841 0.82 NR4A2 (0.57) KMT2AALDH1A1MEN1RAB9ALMNA
SCHEMBL8531445 0.82 PTGS1 (0.64) KMT2AALDH1A1RAB9ALMNANPSR1
SCHEMBL9689491 0.82 KMT2A (0.54) KMT2AALDH1A1MEN1RAB9ALMNA
Hydrochloric Acid SCHEMBL27986091 0.82 KMT2A (0.52) KMT2AALDH1A1MEN1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108752257-B Application of high-valence iodine reagent mediated preparation of indole derivatives 南开大学 2021-05-11 CN disclosed