Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MAP2 | P11137 | 4/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL613136 | 0.84 | LMNA (0.51) | MEN1KMT2AMAP2RXFP1CSF1R | |
| SCHEMBL28553501 | 0.82 | KMT2A (0.61) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL7681481 | 0.82 | LMNA (0.49) | MEN1KMT2AMAP2RXFP1CYP1A2 | |
| SCHEMBL2355240 | 0.81 | NR4A2 (0.63) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL13726361 | 0.79 | ALDH1A1 (0.55) | MEN1KMT2ANPC1RAB9ARXFP1 | |
| SCHEMBL17373720 | 0.79 | ALDH1A1 (0.69) | CSF1RALDH1A1CYP1A2HPGDXBP1 | |
| SCHEMBL6869854 | 0.79 | LMNA (0.49) | MAP2CSF1RCYP1A2HPGDLMNA | |
| SCHEMBL25260242 | 0.78 | ALDH1A1 (0.58) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL28524078 | 0.78 | MEN1 (0.58) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL7002058 | 0.78 | KDM4E (0.67) | MEN1KMT2AMAP2RXFP1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109265386-B | Novel method for synthesizing 3-acylated indole derivative through C-H activation | 四川大学 | 2021-02-09 | — | — | CN | disclosed |