SCHEMBL28553554

SCHEMBL28553554

CC1(C)OB(c2ccc(-c3ccc(-c4ncnc(-c5ccc6ccccc6c5)n4)cc3)cc2)OC1(C)C

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 9/20 0.72
LPL P06858 8/20 0.72
SNCA P37840 1/20 0.40
DGAT1 O75907 1/20 0.40
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 2/20 0.37
MEN1 O00255 1/20 0.37
TP53 P04637 1/20 0.37
CYP1A2 P05177 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HSD17B10 Q99714 1/20 0.37
P4HB P07237 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
IRAK4 Q9NWZ3 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28437249 0.99 LIPG (0.70) LIPGLPLSNCADGAT1KDM4E
SCHEMBL24475152 0.92 LIPG (0.81) LIPGLPLSNCADGAT1KDM4E
SCHEMBL19106579 0.91 LIPG (0.78) LIPGLPLSNCADGAT1KDM4E
SCHEMBL30125490 0.91 LIPG (0.78) LIPGLPLSNCADGAT1KDM4E
SCHEMBL28906129 0.89 LIPG (0.59) LIPGLPLSNCADGAT1KDM4E
SCHEMBL19106578 0.88 LIPG (0.74) LIPGLPLSNCADGAT1KDM4E
SCHEMBL28556209 0.88 LIPG (0.71) LIPGLPLSNCADGAT1P4HB
SCHEMBL23277120 0.88 LIPG (0.71) LIPGLPLSNCADGAT1P4HB
SCHEMBL28551535 0.87 LIPG (0.61) LIPGLPLSNCADGAT1P4HB
SCHEMBL29446659 0.86 LIPG (0.68) LIPGLPLSNCADGAT1P4HB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106661024-B Organic light-emitting compound and organic electroluminescent element using same 索路思高新材料有限公司 2021-04-20 CN disclosed