SCHEMBL28554186

SCHEMBL28554186

Cc1cc2ccccc2c(C)c1C.N=C=O.N=C=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 7/20 0.45
CYP2A6 P11509 3/20 0.45
TSHR P16473 1/20 0.45
ALDH1A1 P00352 6/20 0.39
HSD17B10 Q99714 3/20 0.39
HPGD P15428 3/20 0.39
KDM4E B2RXH2 3/20 0.39
GAA P10253 2/20 0.39
CYP1B1 Q16678 2/20 0.35
HIF1A Q16665 1/20 0.35
BRD4 O60885 1/20 0.35
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
GLA P06280 1/20 0.34
CYP2C19 P33261 1/20 0.34
CCR1 P32246 1/20 0.34
CCR8 P51685 1/20 0.34
TYMP P19971 1/20 0.34
HSP90AA1 P07900 1/20 0.34
HSP90AB1 P08238 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL459684 0.88 CYP1A2 (0.56) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL10630656 0.86 CYP1A2 (0.54) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
Hydrochloric Acid SCHEMBL28848790 0.86 CYP1A2 (0.54) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL10630661 0.86 CYP1A2 (0.54) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
Ammonia Solution, Strong SCHEMBL4639022 0.86 CYP1A2 (0.54) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
Hydrochloric Acid SCHEMBL5928867 0.84 CYP1A2 (0.52) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
Methyl Alcohol SCHEMBL28159335 0.84 CYP1A2 (0.52) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
Bicarbonate SCHEMBL28943553 0.82 ALDH1A1 (0.48) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
Naphthalene SCHEMBL11134608 0.81 ALDH1A1 (0.47) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL11201489 0.78 CYP1A2 (0.76) CYP1A2CYP2A6TSHRALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115916463-A Microspheres containing polymerizable functional groups 株式会社德山 2023-04-04 CN disclosed
CN-115697973-A Sulfonic acid quaternary ammonium salt containing multifunctional active hydrogen group 株式会社德山 2023-02-03 CN disclosed
CN-112625203-B Polyurethane prepolymer composition, polyurethane elastomer, and method for producing same 立大化工股份有限公司 2022-04-19 CN disclosed
CN-112625203-A Polyurethane prepolymer composition, polyurethane elastomer, and method for producing same 立大化工股份有限公司 2021-04-09 CN disclosed