Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | TACR3 | P29371 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28737053 | 0.82 | MEN1 (0.39) | MEN1KMT2ASLC6A3SLC6A2SLC6A4 | |
| SCHEMBL29034607 | 0.81 | DDB1 (0.42) | KMT2ASLC6A3SLC6A2L3MBTL1ALDH1A1 | |
| SCHEMBL19744662 | 0.81 | MEN1 (0.41) | MEN1KMT2ASLC6A3SLC6A2SLC6A4 | |
| SCHEMBL3454133 | 0.80 | MEN1 (0.37) | MEN1KMT2ASLC6A3SLC6A2SLC6A4 | |
| SCHEMBL28695093 | 0.80 | MEN1 (0.37) | MEN1KMT2ASLC6A3SLC6A2SLC6A4 | |
| SCHEMBL28712291 | 0.76 | KMT2A (0.34) | MEN1KMT2ASLC6A3SLC6A2SLC6A4 | |
| SCHEMBL31198221 | 0.74 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL5581649 | 0.74 | SLC6A3 (0.35) | MEN1KMT2ASLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7041565 | 0.73 | CHRM3 (0.33) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL28852266 | 0.72 | HDAC4 (0.31) | NPC1RAB9AHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112689630-A | Novel LXR modulators with bicyclic core moieties | 菲尼克斯-FXR股份有限公司 | 2021-04-20 | — | — | CN | disclosed |