SCHEMBL28554398

SCHEMBL28554398

CS(=O)(=O)c1ccc(C(=O)O)c(Cl)c1CBr.[NaH]

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.40
ATM Q13315 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
HPGD P15428 1/20 0.35
CYP2C19 P33261 1/20 0.35
TSHR P16473 2/20 0.35
ADRA1D P25100 1/20 0.33
ALDH1A1 P00352 3/20 0.32
BCAT2 O15382 1/20 0.32
ALOX15 P16050 1/20 0.32
CASP1 P29466 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4508862 0.98 LMNA (0.41) LMNAATMCYP1A2CYP3A4CYP2D6
SCHEMBL31147083 0.98 LMNA (0.41) LMNAATMCYP1A2CYP3A4CYP2D6
SCHEMBL28913322 0.97 LMNA (0.40) LMNAATMCYP1A2CYP3A4CYP2D6
SCHEMBL31223252 0.86 CYP1A2 (0.36) LMNAATMCYP1A2CYP3A4CYP2D6
SCHEMBL6673408 0.85 CYP1A2 (0.47) LMNAATMCYP1A2CYP3A4CYP2D6
SCHEMBL9076945 0.84 LMNA (0.41) LMNAATMCYP1A2CYP3A4CYP2D6
SCHEMBL28519054 0.84 LMNA (0.41) LMNAATMCYP1A2CYP3A4CYP2D6
Potassium Ion SCHEMBL28912524 0.84 LMNA (0.33) LMNAATMCYP1A2CYP3A4CYP2D6
SCHEMBL28559043 0.84 LMNA (0.33) LMNAATMCYP1A2CYP3A4CYP2D6
SCHEMBL3437073 0.82 CDK1 (0.40) ATMCYP1A2CYP3A4CYP2D6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112645853-A Preparation method of 2-chloro-3-alkoxymethyl-4-methylsulfonylbenzoic acid 江西天宇化工有限公司 2021-04-13 CN disclosed