Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 16/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2711647 | 0.90 | DPP4 (0.58) | GPR119DPP4DPP8DPP9 | |
| SCHEMBL2709916 | 0.87 | DPP4 (0.46) | DPP4KCNH2 | |
| SCHEMBL2708268 | 0.86 | PREP (0.43) | GPR119DPP4PREPDPP8DPP9 | |
| SCHEMBL2711368 | 0.86 | DPP4 (0.56) | DPP4PREPDPP8DPP9 | |
| SCHEMBL2711180 | 0.86 | DPP4 (0.55) | GPR119DPP4PREPDPP8KCNH2 | |
| SCHEMBL3839541 | 0.85 | GPR119 (0.51) | GPR119DPP4FAAHMGLLMAPT | |
| SCHEMBL2707086 | 0.85 | DPP4 (0.61) | DPP4MAPTDPP8DPP7DPP9 | |
| SCHEMBL2709036 | 0.85 | DPP4 (0.62) | DPP4PREPDPP8DPP9 | |
| SCHEMBL2708993 | 0.85 | DPP4 (0.58) | DPP4PREPDPP8DPP9 | |
| SCHEMBL2711860 | 0.84 | DPP4 (0.61) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790725-B2 | Thiazolidine derivatives and medicinal use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-09-07 | — | — | US | disclosed |