Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28554628 | 0.90 | ATM (0.68) | ATMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL28553447 | 0.82 | ATM (0.59) | ATMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL5696416 | 0.79 | ATM (0.61) | ATMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL20552691 | 0.76 | ATM (0.51) | ATMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL20552426 | 0.74 | ATM (0.49) | ATMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL20552451 | 0.73 | ATM (0.48) | ATMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL20551695 | 0.72 | MAPT (0.50) | ATMMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL23625644 | 0.71 | RAB9A (0.65) | RAB9AALDH1A1L3MBTL1TSHR | |
| SCHEMBL20552347 | 0.71 | ABCG2 (0.46) | ALDH1A1SMN1; SMN2TP53LMNA | |
| SCHEMBL23625631 | 0.70 | RAB9A (0.62) | RAB9AALDH1A1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112724141-A | GPR109A protein receptor inhibitor and preparation and application thereof | 南京艾美斐生物医药科技有限公司 | 2021-04-30 | — | — | CN | disclosed |