Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10927730 | 0.81 | GPR84 (0.53) | GPR84FFAR1MAPTMEN1KMT2A | |
| SCHEMBL9262621 | 0.81 | GPR84 (0.68) | GPR84FFAR1MAPTMEN1KMT2A | |
| SCHEMBL29090494 | 0.81 | GPR84 (0.62) | GPR84FFAR1MAPTMEN1KMT2A | |
| SCHEMBL5639751 | 0.80 | GPR84 (0.60) | GPR84FFAR1MAPTMEN1KMT2A | |
| SCHEMBL8213938 | 0.80 | MAPT (0.67) | GPR84FFAR1MAPTMEN1KMT2A | |
| SCHEMBL5641261 | 0.80 | GPR84 (0.60) | GPR84FFAR1MAPTMEN1KMT2A | |
| SCHEMBL31611562 | 0.79 | CYP2D6 (0.54) | GPR84FFAR1MAPTMEN1KMT2A | |
| SCHEMBL9350178 | 0.79 | CYP2D6 (0.54) | GPR84FFAR1MAPTMEN1KMT2A | |
| SCHEMBL28961029 | 0.77 | GPR84 (0.49) | GPR84KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL5642067 | 0.77 | GPR84 (0.56) | GPR84FFAR1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112724171-B | 2-phosphonyl-3-fluorovinyl indole compound and preparation method thereof | 南京林业大学 | 2022-02-08 | — | — | CN | claimed |
| CN-112724171-A | 2-phosphonyl-3-fluorovinyl indole compound and preparation method thereof | 南京林业大学 | 2021-04-30 | — | — | CN | claimed |
| CN-115490628-B | Preparation method of difluoroethanol compound | 五邑大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-115490628-A | Preparation method of difluoroethanol compound | 五邑大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-112724171-B | 2-phosphonyl-3-fluorovinyl indole compound and preparation method thereof | 南京林业大学 | 2022-02-08 | — | — | CN | disclosed |
| CN-112724171-B | 2-phosphonyl-3-fluorovinyl indole compound and preparation method thereof | 南京林业大学 | 2022-02-08 | — | — | CN | disclosed |
| CN-112724171-A | 2-phosphonyl-3-fluorovinyl indole compound and preparation method thereof | 南京林业大学 | 2021-04-30 | — | — | CN | disclosed |
| CN-112724171-A | 2-phosphonyl-3-fluorovinyl indole compound and preparation method thereof | 南京林业大学 | 2021-04-30 | — | — | CN | disclosed |