Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 5/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28570441 | 0.96 | LMNA (0.52) | LMNAMAOBMAOARAB9ANPC1 | |
| SCHEMBL13251240 | 0.81 | MAOB (0.60) | MAOBMAOARAB9ANPC1TSHR | |
| SCHEMBL4758947 | 0.81 | LMNA (0.65) | LMNARAB9ANPC1TSHRMAPT | |
| SCHEMBL594966 | 0.79 | MAOB (0.57) | MAOBMAOARAB9ANPC1TSHR | |
| SCHEMBL11800862 | 0.79 | MAOB (0.51) | MAOBMAOARAB9ANPC1TSHR | |
| SCHEMBL6954739 | 0.77 | MAOB (0.63) | MAOBMAOARAB9ANPC1TSHR | |
| SCHEMBL28960849 | 0.77 | LMNA (0.61) | LMNARAB9ATSHRMAPTSMN1; SMN2 | |
| SCHEMBL7337006 | 0.77 | MAOB (0.63) | MAOBMAOARAB9ANPC1TSHR | |
| SCHEMBL7312572 | 0.77 | LMNA (0.61) | LMNARAB9ATSHRMAPTSMN1; SMN2 | |
| SCHEMBL11807107 | 0.77 | MAOB (0.52) | MAOBMAOARAB9ANPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407801-B | 3, 4-methylenedioxy phenoxy fibrate- (3, 4-methylenedioxy) phenyl ester compound and application thereof in reducing blood fat | 陕西中医药大学 | 2020-12-22 | — | — | CN | disclosed |