Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.44 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | BRD4 | O60885 | 7/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28911635 | 0.89 | STK17B (0.45) | STK17BSTK17ACA12CA1CA2 | |
| SCHEMBL21551137 | 0.85 | STK17B (0.41) | STK17BSTK17ACA12CA1CA2 | |
| SCHEMBL21564565 | 0.84 | STK17B (0.40) | STK17BSTK17ACA12CA1CA2 | |
| SCHEMBL21551136 | 0.84 | STK17B (0.40) | STK17BSTK17ACA12CA1CA2 | |
| SCHEMBL21564397 | 0.77 | BRD4 (0.38) | BRD4DRD2 | |
| SCHEMBL28539414 | 0.72 | CKS1B (0.48) | — | |
| SCHEMBL30931847 | 0.71 | STK17B (0.53) | STK17BSTK17ACA12CA1CA2 | |
| SCHEMBL21564563 | 0.71 | STK17B (0.53) | STK17BSTK17ACA12CA1CA2 | |
| SCHEMBL17155025 | 0.69 | STK17B (0.55) | STK17BSTK17ACA12CA1CA2 | |
| SCHEMBL31080085 | 0.69 | STK17B (0.55) | STK17BSTK17ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384509-B | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-112384509-A | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-02-19 | — | — | CN | disclosed |