Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.45 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 4/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28555951 | 0.89 | STK17B (0.44) | STK17BSTK17ACA12CA1CA2 | |
| SCHEMBL21551137 | 0.84 | STK17B (0.41) | STK17BSTK17ACA12CA1CA2 | |
| SCHEMBL21551136 | 0.83 | STK17B (0.40) | STK17BSTK17ACA12CA1CA2 | |
| SCHEMBL21564565 | 0.83 | STK17B (0.40) | STK17BSTK17ACA12CA1CA2 | |
| SCHEMBL21564397 | 0.76 | BRD4 (0.38) | BRD4DRD2 | |
| SCHEMBL28443979 | 0.73 | ABL1 (0.50) | — | |
| SCHEMBL30931847 | 0.72 | STK17B (0.53) | STK17BSTK17ACA12CA1CA2 | |
| SCHEMBL21564563 | 0.72 | STK17B (0.53) | STK17BSTK17ACA12CA1CA2 | |
| SCHEMBL15036877 | 0.71 | CA1 (0.56) | CA12CA1CA2CA9SUCNR1 | |
| SCHEMBL16169738 | 0.71 | CA1 (0.56) | CA12CA1CA2CA9SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384509-A | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-02-19 | — | — | CN | disclosed |