(Z)-1,2-Diphenylethene

(Z)-1,2-Diphenylethene

SCHEMBL28557293

C(=Cc1ccccc1)c1ccccc1.C(=Cc1ccccc1)c1ccccc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.61
ALDH1A1 P00352 2/20 0.60
NFE2L2 Q16236 3/20 0.57
CYP19A1 P11511 2/20 0.57
MAOA P21397 2/20 0.57
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
CHAT P28329 2/20 0.52
CA1 P00915 1/20 0.52
MGLL Q99685 1/20 0.52
TRPA1 O75762 3/20 0.50
RELA Q04206 2/20 0.50
CYP11B1 P15538 1/20 0.50
CYP11B2 P19099 1/20 0.50
LMNA P02545 1/20 0.50
ALOX5 P09917 1/20 0.50
MAPK1 P28482 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Z)-1,2-Diphenylethene SCHEMBL1892609 1.00 MAOB (0.61) MAOBALDH1A1NFE2L2CYP19A1MAOA
(Z)-1,2-Diphenylethene SCHEMBL1892612 1.00 MAOB (0.61) MAOBALDH1A1NFE2L2CYP19A1MAOA
(Z)-1,2-Diphenylethene SCHEMBL21045987 0.97 MAOB (0.58) MAOBALDH1A1NFE2L2CYP19A1MAOA
SCHEMBL11548255 0.94 CA1 (0.60) MAOBALDH1A1NFE2L2CYP19A1MAOA
SCHEMBL4004892 0.94 CA1 (0.60) MAOBALDH1A1NFE2L2CYP19A1MAOA
SCHEMBL11548251 0.94 CA1 (0.60) MAOBALDH1A1NFE2L2CYP19A1MAOA
SCHEMBL4004894 0.94 CA1 (0.60) MAOBALDH1A1NFE2L2CYP19A1MAOA
SCHEMBL11548873 0.90 MAOB (0.62) MAOBNFE2L2CYP19A1MAOAMEN1
SCHEMBL83380 0.90 MAOB (0.62) MAOBNFE2L2CYP19A1MAOAMEN1
SCHEMBL9171323 0.90 CA1 (0.62) MAOBALDH1A1NFE2L2CYP19A1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112778229-B Method for continuously preparing fluorescent whitening agent 上海合丽亚化工科技有限公司 2022-07-29 CN claimed
CN-112778229-A Method for continuously preparing fluorescent whitening agent 上海合丽亚化工科技有限公司 2021-05-11 CN claimed
CN-110771264-B Light-emitting element, display device, and electronic apparatus 索尼半导体解决方案公司 2022-09-20 CN disclosed