Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK12 | Q9NYV4 | 19/20 | 0.57 |
| ▸ | CCNK | O75909 | 18/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | CCNH | P51946 | 1/20 | 0.43 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28557319 | 1.00 | CDK12 (0.57) | CDK12CCNKMAPK1CCNA2CDK2 | |
| SCHEMBL28551451 | 0.86 | CDK12 (0.57) | CDK12CCNKCCNA2CDK2CDK7 | |
| SCHEMBL28543261 | 0.86 | CCNK (0.60) | CDK12CCNK | |
| SCHEMBL28552948 | 0.86 | CCNK (0.60) | CDK12CCNK | |
| SCHEMBL28543260 | 0.86 | CCNK (0.60) | CDK12CCNK | |
| SCHEMBL28551450 | 0.86 | CDK12 (0.57) | CDK12CCNKCCNA2CDK2CDK7 | |
| SCHEMBL4105243 | 0.84 | EPHX2 (0.46) | CDK12CCNKMAPK1 | |
| SCHEMBL28559025 | 0.83 | CCNK (0.60) | CDK12CCNK | |
| SCHEMBL28559024 | 0.83 | CCNK (0.60) | CDK12CCNK | |
| SCHEMBL28541024 | 0.82 | CCNK (0.60) | CDK12CCNKCCNA2CDK2CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638373-A | Cyclin-dependent kinase inhibitors | 金耐特生物制药公司 | 2021-04-09 | — | — | CN | disclosed |