SCHEMBL28557347

SCHEMBL28557347

ClC(Br)=C(Cl)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
DAO P14920 1/20 0.46
NAPRT Q6XQN6 1/20 0.46
ALDH1A1 P00352 4/20 0.45
HIF1A Q16665 2/20 0.45
CES1 P23141 5/20 0.39
CES2 O00748 4/20 0.39
SRD5A2 P31213 1/20 0.39
ESR1 P03372 1/20 0.37
GSK3B P49841 2/20 0.37
MAPK1 P28482 2/20 0.37
TRPA1 O75762 1/20 0.37
PTPN1 P18031 1/20 0.37
CYP3A4 P08684 2/20 0.36
MAPT P10636 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
F2 P00734 1/20 0.36
F10 P00742 1/20 0.36
F12 P00748 1/20 0.36
F7 P08709 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28858517 1.00 TSHR (0.46) TSHRDAONAPRTALDH1A1HIF1A
SCHEMBL28858578 0.83 TSHR (0.46) TSHRDAONAPRTALDH1A1HIF1A
SCHEMBL3940728 0.82 TSHR (0.56) TSHRDAONAPRTALDH1A1HIF1A
SCHEMBL3940726 0.82 TSHR (0.56) TSHRDAONAPRTALDH1A1HIF1A
SCHEMBL28858554 0.79 ALDH1A1 (0.42) TSHRDAONAPRTALDH1A1HIF1A
SCHEMBL28858549 0.79 ALDH1A1 (0.42) TSHRDAONAPRTALDH1A1HIF1A
SCHEMBL28858448 0.78 TSHR (0.46) TSHRDAONAPRTALDH1A1HIF1A
SCHEMBL28858483 0.78 CES1 (0.39) TSHRDAONAPRTALDH1A1HIF1A
SCHEMBL11229482 0.78 CES1 (0.39) TSHRDAONAPRTALDH1A1HIF1A
SCHEMBL9226118 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115197046-A Halogenation method of unsaturated hydrocarbon 华南理工大学 2022-10-18 CN disclosed
CN-106459449-B Styrene-based biaxially stretched sheet, biaxially stretched sheet with antifogging agent layer, packaging container, and heat cooking method 电化株式会社 2021-04-27 CN disclosed