Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 12/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 12/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 12/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 12/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 12/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 12/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL925258 | 0.82 | KDM4E (0.47) | CNR2CNR1KDM4EALDH1A1GAA | |
| SCHEMBL14107130 | 0.81 | KDM4E (0.46) | CNR2CNR1KDM4EALDH1A1GAA | |
| SCHEMBL15747195 | 0.78 | KDM4E (0.44) | CNR2CNR1KDM4EALDH1A1GAA | |
| SCHEMBL15024749 | 0.78 | ALDH1A1 (0.40) | CNR2CNR1KDM4EALDH1A1GAA | |
| SCHEMBL28215696 | 0.77 | NR4A2 (0.46) | CNR2CNR1KDM4EALDH1A1GAA | |
| SCHEMBL28559509 | 0.76 | PSEN1 (0.41) | CNR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9976726 | 0.75 | KDM4E (0.43) | CNR2CNR1KDM4EALDH1A1GAA | |
| SCHEMBL20987436 | 0.75 | CNR2 (0.47) | CNR2CNR1KDM4EALDH1A1GAA | |
| SCHEMBL20987483 | 0.74 | CNR2 (0.47) | CNR2CNR1KDM4EALDH1A1GAA | |
| SCHEMBL15144206 | 0.73 | ALDH1A1 (0.35) | CNR2CNR1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109161004-B | Copolymer based on pyrrolodiindole and preparation method and application thereof | 湘潭大学 | 2021-05-04 | — | — | CN | disclosed |