SCHEMBL28558391

SCHEMBL28558391

CC(C)(C)OC(=O)NOC(=O)C1CC(C(=O)O)C1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BTK Q06187 1/20 0.49
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.35
MAPK1 P28482 1/20 0.35
CTSK P43235 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
POLB P06746 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
KDM1A O60341 1/20 0.32
MAOB P27338 1/20 0.32
GAA P10253 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28558390 0.93 BTK (0.42) BTKKMT2AMEN1MAPK1CTSK
SCHEMBL2540692 0.82 BTK (0.42) BTKKMT2AMEN1MAPK1CTSK
SCHEMBL28396160 0.81 NR1H2 (0.44) BTKKMT2AMEN1MAPK1CTSK
SCHEMBL3641879 0.80 BTK (0.46) BTKKMT2AMAPK1POLB
SCHEMBL28473594 0.80 BTK (0.46) BTKKMT2AMAPK1POLB
SCHEMBL1297489 0.80 BTK (0.46) BTKKMT2AMAPK1POLB
SCHEMBL1771267 0.79 BTK (0.51) BTKKMT2AMEN1CTSKCA12
SCHEMBL4706132 0.79 BTK (0.47) BTKKMT2AMEN1CTSKALDH1A1
SCHEMBL19204911 0.78 NFKB1 (0.37) BTKKMT2AMEN1MAPK1CTSK
SCHEMBL27988318 0.78 GAA (0.42) BTKKMT2AMEN1MAPK1CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112703447-A Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal display element, diamine, method for producing diamine, and polymer 日产化学株式会社 2021-04-23 CN disclosed