Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28549563 | 0.98 | TRPV4 (0.47) | TRPV4HDAC4DGAT1PDE10AMRGPRX4 | |
| SCHEMBL5484094 | 0.81 | TRPV4 (0.48) | TRPV4KCNH2 | |
| SCHEMBL627545 | 0.81 | TRPV4 (0.48) | TRPV4HDAC4MRGPRX4TRPV1GRM4 | |
| SCHEMBL30395883 | 0.81 | TRPV4 (0.48) | TRPV4HDAC4MRGPRX4TRPV1GRM4 | |
| Hydrochloric Acid SCHEMBL30936029 | 0.79 | TRPV4 (0.47) | TRPV4 | |
| Hydrochloric Acid SCHEMBL5125109 | 0.79 | TRPV4 (0.47) | TRPV4HDAC4MRGPRX4TRPV1GRM4 | |
| Hydrochloric Acid SCHEMBL4394798 | 0.79 | TRPV4 (0.47) | TRPV4 | |
| Hydrochloric Acid SCHEMBL25304395 | 0.78 | TRPV4 (0.46) | TRPV4KCNH2 | |
| SCHEMBL2538969 | 0.78 | TRPV4 (0.46) | TRPV4HDAC4TRPV1SLC6A3KCNH2 | |
| SCHEMBL4248074 | 0.78 | TRPV4 (0.46) | TRPV4MRGPRX4TRPV1GRM4CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112739689-B | Fluorine-containing pyrimidine compound and method for producing same | 优迈特株式会社 | 2022-06-03 | — | — | CN | disclosed |
| CN-112739689-A | Fluorine-containing pyrimidine compound and method for producing same | 优迈特株式会社 | 2021-04-30 | — | — | CN | disclosed |