Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 4/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 2/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2633968 | 1.00 | PARP15 (0.38) | PARP15PARP10PARP2SLC1A3SLC1A2 | |
| SCHEMBL2633967 | 1.00 | PARP15 (0.38) | PARP15PARP10PARP2SLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL28568896 | 0.98 | PARP15 (0.37) | PARP15PARP10PARP2SLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL28568895 | 0.98 | PARP15 (0.37) | PARP15PARP10PARP2SLC1A3SLC1A2 | |
| SCHEMBL111361 | 0.91 | — | — | |
| SCHEMBL30427433 | 0.91 | PARP15 (0.42) | PARP15PARP10PARP2SLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL28974199 | 0.89 | — | — | |
| SCHEMBL28479090 | 0.83 | PARP15 (0.38) | PARP15PARP10PARP2SLC1A3SLC1A2 | |
| SCHEMBL5861626 | 0.83 | LMNA (0.48) | PARP15PARP10PARP2SLC1A3SLC1A2 | |
| SCHEMBL28615281 | 0.83 | PARP15 (0.38) | PARP15PARP10PARP2SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118103074-A | Cytotoxic targeting chimeras for CCR2 expressing cells | 葛兰素史克知识产权发展有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-107793360-B | Indoleamine 2, 3-dioxygenase inhibitor and application thereof | 南京药捷安康生物科技有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-107793360-A | Indoleamine 2,3 dioxygenase inhibitors and application | 南京药捷安康生物科技有限公司 | 2018-03-13 | — | — | CN | disclosed |