Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29444020 | 0.90 | OPRD1 (0.49) | F2OPRD1PREPKMT2AALDH1A1 | |
| SCHEMBL21462327 | 0.90 | OPRD1 (0.49) | F2OPRD1PREPKMT2AALDH1A1 | |
| SCHEMBL31258873 | 0.90 | OPRD1 (0.49) | F2OPRD1PREPKMT2AALDH1A1 | |
| SCHEMBL30034009 | 0.87 | OPRD1 (0.47) | F2OPRD1PREPKMT2AALDH1A1 | |
| SCHEMBL28665306 | 0.87 | OPRD1 (0.48) | F2OPRD1PREPKMT2AALDH1A1 | |
| SCHEMBL30366864 | 0.87 | OPRD1 (0.48) | F2OPRD1PREPKMT2AALDH1A1 | |
| SCHEMBL17210440 | 0.86 | KLK5 (0.46) | F2OPRD1PREPKMT2AALDH1A1 | |
| SCHEMBL15083158 | 0.86 | PDK2 (0.45) | F2PREPKMT2AALDH1A1ACE | |
| SCHEMBL15803221 | 0.86 | PDK2 (0.45) | F2PREPKMT2AALDH1A1ACE | |
| SCHEMBL24378516 | 0.85 | OPRD1 (0.48) | F2OPRD1PREPKMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112851536-B | Method for constructing amide bond by clicking pyrimidine condensing agent and application of method in amide and polypeptide synthesis | 兰州大学 | 2022-02-25 | — | — | CN | disclosed |
| CN-112851536-A | Method for constructing amide bond by clicking pyrimidine condensing agent and application of method in amide and polypeptide synthesis | 兰州大学 | 2021-05-28 | — | — | CN | disclosed |