SCHEMBL28559768

SCHEMBL28559768

C=C(C)C(=O)n1c(N)nc2nc[nH]c2c1=O

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MGMT P16455 4/20 0.41
CDK2 P24941 4/20 0.41
CDK1 P06493 3/20 0.41
CCNB1 P14635 3/20 0.41
CCNA2 P20248 3/20 0.41
CCNA1 P78396 3/20 0.41
GDA Q9Y2T3 2/20 0.40
PNP P00491 1/20 0.40
DPP4 P27487 1/20 0.38
PDPK1 O15530 1/20 0.36
CYP1A2 P05177 1/20 0.36
MAP3K5 Q99683 1/20 0.35
PDE4A P27815 2/20 0.34
PDE4B Q07343 2/20 0.34
PDE4C Q08493 2/20 0.34
PDE4D Q08499 2/20 0.34
ALDH1A1 P00352 1/20 0.34
ATAD2 Q6PL18 1/20 0.34
HRH4 Q9H3N8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL218669 0.86 MGMT (0.45) MGMTCDK2CDK1CCNB1CCNA2
Bromide SCHEMBL8165615 0.85 MGMT (0.44) MGMTCDK2CDK1CCNB1CCNA2
SCHEMBL6821773 0.81 PNP (0.45) MGMTCDK2GDAPNPDPP4
SCHEMBL453204 0.80 CYP1A2 (0.41) MGMTCDK2CDK1CCNB1CCNA2
SCHEMBL28627686 0.80 PNP (0.41) MGMTCDK2CDK1CCNB1CCNA2
SCHEMBL8843878 0.77 PDE4A (0.43) MGMTCDK2CDK1CCNB1CCNA2
SCHEMBL3072987 0.76 MGMT (0.45) MGMTCDK2CDK1CCNB1CCNA2
Acetic Acid SCHEMBL5323943 0.76 MGMT (0.44) MGMTCDK2CDK1CCNB1CCNA2
SCHEMBL6265538 0.76 MGMT (0.47) MGMTCDK2CDK1CCNB1CCNA2
SCHEMBL5694191 0.75 NPC1 (0.51) MGMTCDK2CDK1CCNB1CCNA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112574376-B Antibacterial polyurethane resin and preparation method thereof 万华化学集团股份有限公司 2022-09-16 CN disclosed
CN-112574376-A Antibacterial polyurethane resin and preparation method thereof 万华化学集团股份有限公司 2021-03-30 CN disclosed