Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 4/20 | 0.45 |
| ▸ | CDK1 | P06493 | 9/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 9/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 9/20 | 0.40 |
| ▸ | CDK2 | P24941 | 9/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 9/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.36 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843878 | 0.83 | PDE4A (0.43) | MGMTCDK1CCNB1CCNA2CDK2 | |
| SCHEMBL5694108 | 0.83 | MEN1 (0.41) | MGMTCDK1CCNB1CCNA2CDK2 | |
| SCHEMBL16401840 | 0.81 | FKBP1A (0.42) | MGMTCDK1CCNB1CCNA2CDK2 | |
| SCHEMBL218669 | 0.81 | MGMT (0.45) | MGMTCDK1CCNB1CCNA2CDK2 | |
| Bromide SCHEMBL8165615 | 0.80 | MGMT (0.44) | MGMTCDK1CCNB1CCNA2CDK2 | |
| SCHEMBL3072977 | 0.80 | MGMT (0.32) | MGMTPDE4AADORA2AADORA2BPDE4B | |
| SCHEMBL6821773 | 0.79 | PNP (0.45) | MGMTCDK2PNPDPP4GDA | |
| SCHEMBL5347878 | 0.79 | CDK1 (0.45) | MGMTCDK1CCNB1CCNA2CDK2 | |
| Benzene SCHEMBL8024450 | 0.79 | MGMT (0.43) | MGMTCDK1CCNB1CCNA2CDK2 | |
| SCHEMBL28368763 | 0.78 | PNP (0.45) | MGMTCDK1CCNB1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790843-B2 | Cypin polypeptide and fragments thereof | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2010-09-07 | — | — | US | disclosed |
| US-20080182970-A1 | Using cypin in assays, diagnostics and treatment of cognitive disorders | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2008-07-31 | — | — | US | disclosed |
| US-7338769-B2 | Methods for identifying agonists of cypin | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2008-03-04 | — | — | US | disclosed |
| US-20050214822-A1 | Using cypin in assays, diagnostics and treatment of cognitive disorders | RUTGERS, THE STATE UNIVERSITY OF NEV | 2005-09-29 | — | — | US | disclosed |