Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 14/20 | 0.56 |
| ▸ | THRA | P10827 | 14/20 | 0.54 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21749554 | 0.85 | THRB (0.59) | THRBTHRACRHR1 | |
| SCHEMBL28912595 | 0.80 | THRB (0.54) | THRBTHRACRHR1 | |
| SCHEMBL21840342 | 0.79 | THRB (0.54) | THRBTHRA | |
| SCHEMBL21749368 | 0.79 | THRB (0.65) | THRBTHRA | |
| SCHEMBL21749357 | 0.77 | THRB (0.52) | THRBTHRA | |
| SCHEMBL21840291 | 0.76 | THRB (0.55) | THRBTHRA | |
| SCHEMBL21749551 | 0.76 | THRB (0.49) | THRBTHRA | |
| SCHEMBL21840288 | 0.76 | THRB (0.55) | THRBTHRA | |
| SCHEMBL28913436 | 0.76 | THRB (0.62) | THRBTHRA | |
| SCHEMBL21749553 | 0.75 | THRB (0.58) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805005-A | Thyroxine receptor beta agonist compounds | 拓臻股份有限公司 | 2021-05-14 | — | — | CN | disclosed |