SCHEMBL28560757

SCHEMBL28560757

CC(=O)C1=C(O)C(Cc2ccc(O)cc2)NC1=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR0B1 P51843 1/20 0.54
KDM4E B2RXH2 2/20 0.43
CAPN1 P07384 1/20 0.41
GAA P10253 2/20 0.40
F13A1 P00488 1/20 0.35
CACNA1G O43497 1/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
KDM1A O60341 1/20 0.34
DRD2 P14416 1/20 0.34
DRD4 P21917 1/20 0.34
PPARG P37231 1/20 0.34
ITGB1 P05556 2/20 0.34
ITGA4 P13612 2/20 0.34
MLNR O43193 2/20 0.34
BCHE P06276 1/20 0.33
ANPEP P15144 1/20 0.33
LNPEP Q9UIQ6 1/20 0.33
CA2 P00918 1/20 0.33
CAMK2A Q9UQM7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28550403 0.88 NR0B1 (0.52) NR0B1KDM4EGAACACNA1GPPARG
SCHEMBL28620615 0.88 NR0B1 (0.69) NR0B1KDM4EGAA
SCHEMBL10007676 0.75 KDM4E (0.56) NR0B1KDM4E
SCHEMBL4246713 0.75 NR0B1 (0.64) NR0B1GAA
SCHEMBL4246061 0.75 NR0B1 (0.50) NR0B1CACNA1GPPARG
SCHEMBL28557461 0.74 NR0B1 (0.52) NR0B1KDM4EGAA
SCHEMBL4241297 0.73 NR0B1 (0.46) NR0B1KDM4EGAACACNA1G
SCHEMBL13399253 0.73 GAA (0.50) CAPN1GAAESR1ESR2KDM1A
SCHEMBL13399671 0.73 GAA (0.50) CAPN1GAAESR1ESR2KDM1A
SCHEMBL13399579 0.73 GAA (0.50) CAPN1GAAESR1ESR2KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112778188-A Preparation method of alternaria tenuifolia keto acid and derivatives thereof 安徽农业大学 2021-05-11 CN disclosed