Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR0B1 | P51843 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28620615 | 0.88 | NR0B1 (0.69) | NR0B1GAAPOLBCYP1A2CYP3A4 | |
| SCHEMBL4246061 | 0.86 | NR0B1 (0.50) | NR0B1ALOX15 | |
| SCHEMBL4241441 | 0.84 | NR0B1 (0.48) | NR0B1POLB | |
| SCHEMBL4244807 | 0.84 | NR0B1 (0.61) | NR0B1PLA2G10PLA2G5ALOX15 | |
| SCHEMBL8200513 | 0.79 | NR0B1 (0.48) | NR0B1GAAPOLBCYP1A2CYP3A4 | |
| SCHEMBL29464991 | 0.79 | NR0B1 (1.00) | NR0B1GAAPOLBCYP1A2CYP3A4 | |
| SCHEMBL13743754 | 0.79 | NR0B1 (0.52) | NR0B1GAAPOLBALOX15NPSR1 | |
| SCHEMBL13743665 | 0.79 | NR0B1 (0.52) | NR0B1GAAPOLBHDAC1HDAC6 | |
| SCHEMBL13743929 | 0.78 | NR0B1 (0.48) | NR0B1HDAC1HDAC6ALOX15NPSR1 | |
| SCHEMBL4238539 | 0.78 | NR0B1 (0.51) | NR0B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | HURLEY TIMOTHY BRIAN | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | FDPS, UMPS, GGPS1 | NR0B1 2001/4885GAA 632/4885POLB 470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.