Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | L3MBTL3 | Q96JM7 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3810047 | 0.97 | — | — | |
| SCHEMBL3278728 | 0.94 | HTR6 (0.56) | HTR6L3MBTL3L3MBTL1FYNMBTD1 | |
| Hydrochloric Acid SCHEMBL22607680 | 0.94 | HTR6 (0.56) | HTR6L3MBTL3L3MBTL1FYNMBTD1 | |
| SCHEMBL20365049 | 0.94 | HTR6 (0.56) | HTR6L3MBTL3L3MBTL1FYNMBTD1 | |
| Hydrochloric Acid SCHEMBL3258445 | 0.94 | HTR6 (0.56) | HTR6L3MBTL3L3MBTL1FYNMBTD1 | |
| SCHEMBL2475741 | 0.94 | HTR6 (0.56) | HTR6L3MBTL3L3MBTL1FYNMBTD1 | |
| Hydrochloric Acid SCHEMBL7814587 | 0.92 | HTR6 (0.54) | HTR6L3MBTL3L3MBTL1FYNMBTD1 | |
| Hydrochloric Acid SCHEMBL29082713 | 0.92 | HTR6 (0.54) | HTR6L3MBTL3L3MBTL1FYNMBTD1 | |
| SCHEMBL3056808 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL31603559 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112672995-A | Novel sulfonamide urea compounds | 英夫拉索姆有限公司 | 2021-04-16 | — | — | CN | disclosed |