Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11909441 | 1.00 | MAPT (0.51) | MAPTRECQLALDH1A1MAPK1LMNA | |
| SCHEMBL4439231 | 0.89 | MAPT (0.55) | MAPTRECQLALDH1A1MAPK1LMNA | |
| SCHEMBL4434482 | 0.89 | POLB (0.48) | MAPTALDH1A1LMNAGAAPOLB | |
| SCHEMBL4436306 | 0.88 | MAPK1 (0.55) | MAPTALDH1A1MAPK1LMNAGAA | |
| SCHEMBL28913476 | 0.88 | MAPT (0.49) | MAPTALDH1A1LMNAGAAPOLB | |
| SCHEMBL28913479 | 0.88 | MAPT (0.49) | MAPTALDH1A1LMNAGAAPOLB | |
| SCHEMBL4436140 | 0.87 | POLB (0.54) | MAPTALDH1A1MAPK1LMNAHPGD | |
| SCHEMBL10188551 | 0.87 | MAPT (0.58) | MAPTALDH1A1MAPK1LMNAHPGD | |
| SCHEMBL2976956 | 0.86 | LMNA (0.63) | MAPTALDH1A1MAPK1LMNAGAA | |
| SCHEMBL2976958 | 0.86 | LMNA (0.63) | MAPTALDH1A1MAPK1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108373476-B | Kinase inhibitor and preparation and application thereof | 成都地奥制药集团有限公司 | 2021-06-01 | — | — | CN | disclosed |