SCHEMBL28560972

SCHEMBL28560972

C=Cc1cccc(C(=C)C)c1C=C

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
MEN1 O00255 1/20 0.30
CYP3A4 P08684 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28566959 0.87 TP53 (0.32)
SCHEMBL16959038 0.86 ALDH1A1 (0.35) ALDH1A1
SCHEMBL16952511 0.82 ALDH1A1 (0.33) ALDH1A1
SCHEMBL1645454 0.82 MAPT (0.33) ALDH1A1MEN1KMT2A
SCHEMBL489258 0.81 ALDH1A1 (0.43) ALDH1A1MEN1CYP3A4KMT2A
SCHEMBL9246872 0.81 ALDH1A1 (0.43) ALDH1A1MEN1CYP3A4KMT2A
SCHEMBL1683154 0.80 ALDH1A1 (0.34) ALDH1A1MEN1CYP3A4KMT2A
SCHEMBL11773820 0.80 TTR (0.37) ALDH1A1MEN1KMT2A
SCHEMBL16954095 0.79 ALDH1A1 (0.31) ALDH1A1
SCHEMBL16952690 0.78 ERN1 (0.31) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109776358-B Polyalkenyl aryl isocyanate and preparation method and application thereof 万华化学集团股份有限公司 2021-05-14 CN claimed
CN-109776358-B Polyalkenyl aryl isocyanate and preparation method and application thereof 万华化学集团股份有限公司 2021-05-14 CN disclosed
CN-109776358-A A kind of polyene-based aromatic isocyanate and its preparation method and application 万华化学集团股份有限公司 2019-05-21 CN disclosed