Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL12 | P48061 | 1/20 | 0.61 |
| ▸ | CYP1A1 | P04798 | 11/20 | 0.60 |
| ▸ | CYP1B1 | Q16678 | 11/20 | 0.60 |
| ▸ | DPP4 | P27487 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | KRAS | P01116 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28561633 | 1.00 | CXCL12 (0.61) | CXCL12CYP1A1CYP1B1DPP4MAOB | |
| SCHEMBL28561734 | 0.88 | KRAS (0.61) | CXCL12ABCG2KRASALDH1A1ATM | |
| SCHEMBL28561736 | 0.88 | KRAS (0.61) | CXCL12ABCG2KRASALDH1A1ATM | |
| SCHEMBL27816898 | 0.78 | KRAS (0.67) | CXCL12DPP4MAOBABCG2KRAS | |
| SCHEMBL6714554 | 0.77 | TNFRSF1A (0.59) | ABCG2KRASALDH1A1SMN1; SMN2TUBB4A | |
| SCHEMBL27860092 | 0.77 | TNFRSF1A (0.59) | ABCG2KRASALDH1A1SMN1; SMN2TUBB4A | |
| SCHEMBL25195001 | 0.76 | CXCL12 (1.00) | CXCL12CYP1A1CYP1B1DPP4MAOB | |
| SCHEMBL25190964 | 0.74 | CXCL12 (0.82) | CXCL12CYP1A1CYP1B1DPP4MAOB | |
| SCHEMBL30384244 | 0.74 | CXCL12 (0.82) | CXCL12CYP1A1CYP1B1DPP4MAOB | |
| SCHEMBL25197205 | 0.74 | CXCL12 (0.82) | CXCL12CYP1A1CYP1B1DPP4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112110889-B | Scutellarin aglycone derivative, preparation method and application thereof | 昆明龙津药业股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-112110889-A | Scutellarin aglycone derivative, preparation method and application thereof | 昆明龙津药业股份有限公司 | 2020-12-22 | — | — | CN | disclosed |