Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | F7 | P08709 | 3/20 | 0.38 |
| ▸ | F3 | P13726 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11327956 | 0.94 | ALDH1A1 (0.50) | GRIK1GRIK2FPR2ALDH1A1CYP19A1 | |
| SCHEMBL5379672 | 0.87 | FFAR1 (0.35) | GRIK1GRIK2FFAR1TDP1BHMT | |
| SCHEMBL5379668 | 0.87 | FFAR1 (0.35) | GRIK1GRIK2FFAR1TDP1BHMT | |
| SCHEMBL10299824 | 0.84 | CACNA2D1 (0.38) | GRIK1ALDH1A1MAPTBLMTDP1 | |
| SCHEMBL28588544 | 0.83 | FFAR1 (0.38) | CYP19A1MAPTPPARGFFAR1F7 | |
| SCHEMBL29107159 | 0.83 | ALDH1A1 (0.52) | ALDH1A1MAPTALOX15TDP1BHMT | |
| SCHEMBL11305054 | 0.80 | F7 (0.52) | ALDH1A1CYP19A1MAPTPPARGFFAR1 | |
| SCHEMBL11305067 | 0.80 | F7 (0.52) | ALDH1A1CYP19A1MAPTPPARGFFAR1 | |
| SCHEMBL21986677 | 0.80 | GRIK1 (0.41) | GRIK1GRIK2TDP1BHMTSLC22A6 | |
| SCHEMBL18951927 | 0.79 | ALDH1A1 (0.47) | ALDH1A1CYP19A1MAPTPPARGOXER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107848953-B | Fused ring gamma-amino acid derivative, preparation method and application thereof in medicine | 四川海思科制药有限公司 | 2021-05-18 | — | — | CN | disclosed |