Glutamic Acid

Glutamic Acid

SCHEMBL28561963

N[C@@H](CCC(=O)O)C(=O)O.c1c[nH]cn1.c1c[nH]cn1

nearest known ligand 0.58

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 2/20 0.58
GRM6 O15303 2/20 0.58
GRM7 Q14831 2/20 0.58
GRM4 Q14833 2/20 0.58
GRIN2D O15399 1/20 0.58
GRIN3B O60391 1/20 0.58
GSR P00390 1/20 0.58
CYP1A2 P05177 1/20 0.58
GRIK1 P39086 1/20 0.58
GRM5 P41594 1/20 0.58
GRIA1 P42261 1/20 0.58
GRIA2 P42262 1/20 0.58
GRIA3 P42263 1/20 0.58
SLC1A3 P43003 1/20 0.58
SLC1A2 P43004 1/20 0.58
SLC1A1 P43005 1/20 0.58
GRIA4 P48058 1/20 0.58
GRIN1 Q05586 1/20 0.58
GRIN2A Q12879 1/20 0.58
GRIK2 Q13002 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
D-Glutamate SCHEMBL28154228 1.00 GRM8 (0.58) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL28561964 1.00 GRM8 (0.58) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL28033874 0.98 GRM8 (0.56) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL28033315 0.98 GRM8 (0.56) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL27996480 0.97 GRM8 (0.55) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL29281665 0.86 GRM8 (0.41) GRM8GRM6GRM7GRM4GRIN2D
Norvaline SCHEMBL29109613 0.84 SLC1A2 (0.42) GRM8GRM6GRM7GRM4GRIN2D
Aspartic Acid SCHEMBL28155193 0.83 ALDH1A1 (0.45) GRM8GRM6GRM7GRM4GRIN2D
Ornithine SCHEMBL27825297 0.83 GSR (0.53) GSRCYP1A2ALDH1A1FKBP5CYP3A4
Ornithine Aketoglutarate SCHEMBL27825301 0.83 GSR (0.53) GSRCYP1A2ALDH1A1FKBP5CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112058231-A Method for preparing porous biochar by low-temperature pyrolysis of ionic liquid modified waste biomass, porous biochar and application of porous biochar 上海理工大学 2020-12-11 CN disclosed