Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | TACR2 | P21452 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28562183 | 0.80 | HRH1 (0.49) | POLBMAPTSMN1; SMN2KCNH2HTR2B | |
| SCHEMBL993093 | 0.79 | HTR2B (0.55) | POLBMAPTSMN1; SMN2KCNH2HTR2B | |
| SCHEMBL14916479 | 0.79 | KCNH2 (0.51) | POLBMAPTSMN1; SMN2KCNH2HTR2B | |
| SCHEMBL992242 | 0.78 | HTR2B (0.58) | MAPTSMN1; SMN2KCNH2HTR2BALDH1A1 | |
| SCHEMBL8367704 | 0.77 | HRH1 (0.69) | KCNH2TACR2 | |
| SCHEMBL662101 | 0.75 | PARP1 (0.64) | KCNH2HTR2BALDH1A1PARP1CHRNA7 | |
| SCHEMBL17888861 | 0.74 | HTR2B (0.62) | HTR2BCHRNA7 | |
| SCHEMBL17888844 | 0.73 | HTR2B (0.59) | POLBMAPTSMN1; SMN2HTR2BHSD17B10 | |
| SCHEMBL28050009 | 0.73 | HTR2B (0.49) | POLBMAPTKCNH2HTR2BHSD17B10 | |
| SCHEMBL2546943 | 0.73 | CACNA1H (0.61) | POLBMAPTHTR2BHSD17B10TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110903278-B | Preparation method of bilastine | 山东罗欣药业集团恒欣药业有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-112110893-A | Preparation method of bilastine | 山东齐环医药科技有限公司 | 2020-12-22 | — | — | CN | disclosed |