Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14916479 | 0.92 | KCNH2 (0.51) | HRH1HTR2BPOLBMAPTHSD17B10 | |
| SCHEMBL993093 | 0.89 | HTR2B (0.55) | HRH1HTR2BPOLBMAPTHSD17B10 | |
| SCHEMBL992242 | 0.85 | HTR2B (0.58) | HRH1HTR2BMAPTSMN1; SMN2KCNH2 | |
| SCHEMBL28562199 | 0.80 | POLB (0.52) | HTR2BPOLBMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL991771 | 0.79 | HRH1 (0.79) | HRH1KCNH2 | |
| SCHEMBL30307024 | 0.79 | HRH1 (0.79) | HRH1KCNH2 | |
| SCHEMBL28050009 | 0.77 | HTR2B (0.49) | HRH1HTR2BPOLBMAPTHSD17B10 | |
| SCHEMBL19924942 | 0.75 | POLB (0.64) | HTR2BPOLBMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL21815504 | 0.75 | HTR2B (0.47) | HRH1HTR2BPOLBMAPTHSD17B10 | |
| SCHEMBL8296045 | 0.74 | HTR2B (0.73) | HTR2BPOLBMAPTSMN1; SMN2PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112110893-A | Preparation method of bilastine | 山东齐环医药科技有限公司 | 2020-12-22 | — | — | CN | claimed |
| CN-112110893-A | Preparation method of bilastine | 山东齐环医药科技有限公司 | 2020-12-22 | — | — | CN | disclosed |