Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5106211 | 0.81 | AKR1B1 (0.41) | L3MBTL1ALDH1A1MAPTPOLBKDM4E | |
| SCHEMBL6035740 | 0.81 | TSHR (0.40) | ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL5120016 | 0.78 | CYP4F2 (0.49) | L3MBTL1ALDH1A1MAPTGAA | |
| SCHEMBL23398685 | 0.76 | PTPN1 (0.35) | — | |
| SCHEMBL20448188 | 0.76 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1MAPTNPSR1GAA | |
| SCHEMBL23399118 | 0.73 | TYR (0.40) | MAPTNPSR1GAAKDM4ENPC1 | |
| SCHEMBL24852679 | 0.73 | HDAC6 (0.45) | L3MBTL1ALDH1A1MAPTNPSR1GAA | |
| SCHEMBL25637992 | 0.71 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1MAPTNPSR1GAA | |
| SCHEMBL10626243 | 0.70 | FFAR1 (0.41) | L3MBTL1ALDH1A1MAPTNPSR1HDAC6 | |
| SCHEMBL6642192 | 0.70 | GAA (0.38) | L3MBTL1ALDH1A1NPSR1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112062720-B | Continuous preparation method of 1-methyl-3-hydroxypyrazole-4-carboxylic acid ethyl ester | 江苏七洲绿色化工股份有限公司 | 2022-08-16 | — | — | CN | claimed |
| CN-112062720-A | Continuous preparation method of 1-methyl-3-hydroxypyrazole-4-carboxylic acid ethyl ester | 江苏七洲绿色化工股份有限公司 | 2020-12-11 | — | — | CN | claimed |
| CN-112062720-B | Continuous preparation method of 1-methyl-3-hydroxypyrazole-4-carboxylic acid ethyl ester | 江苏七洲绿色化工股份有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-112062720-B | Continuous preparation method of 1-methyl-3-hydroxypyrazole-4-carboxylic acid ethyl ester | 江苏七洲绿色化工股份有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-112062720-A | Continuous preparation method of 1-methyl-3-hydroxypyrazole-4-carboxylic acid ethyl ester | 江苏七洲绿色化工股份有限公司 | 2020-12-11 | — | — | CN | disclosed |
| CN-112062720-A | Continuous preparation method of 1-methyl-3-hydroxypyrazole-4-carboxylic acid ethyl ester | 江苏七洲绿色化工股份有限公司 | 2020-12-11 | — | — | CN | disclosed |