⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28535859 | 0.97 | — | — | |
| SCHEMBL27839352 | 0.97 | — | — | |
| SCHEMBL114520 | 0.73 | ALDH1A1 (0.41) | — | |
| SCHEMBL28263582 | 0.71 | ALDH1A1 (0.39) | — | |
| SCHEMBL577100 | 0.71 | — | — | |
| SCHEMBL27831111 | 0.71 | ALDH1A1 (0.39) | — | |
| SCHEMBL27543204 | 0.71 | ALDH1A1 (0.39) | — | |
| SCHEMBL114521 | 0.71 | — | — | |
| SCHEMBL28394309 | 0.71 | — | — | |
| SCHEMBL1947040 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321784-A | Bulk polymer and preparation method and application thereof | 联泓(江苏)新材料研究院有限公司 | 2021-02-05 | — | — | CN | claimed |
| EP-1594884-B1 | ANTITUMORAL 18A-HOMOESTRA-1,3,5(10)-TRIEN-3-YL 2-SUBSTITUTED SULFAMATES | STERIX LTD (GB) | 2010-01-13 | — | — | EP | claimed |
| US-20090221841-A1 | 2-SUBSTITUTED ESTRA-1,3,5(10)-TRIENE-3-YL SULFAMATE WITH AN ANTI-TUMOUR ACTION | STERIX LIMITED (GB) | 2009-09-03 | — | — | US | claimed |
| EP-1594886-B1 | ANTITUMORAL D-HOMOESTRA-1, 3, 5 (10)-TRIEN-3-YL 2-SUBSTITUTED SULFAMATES | STERIX LTD (GB) | 2008-08-27 | — | — | EP | claimed |
| US-7244762-B2 | For therapy of prostate cancer | STERIX LIMITED (GB) | 2007-07-17 | — | — | US | claimed |
| US-20060154985-A1 | Antitumoral d-homoestra-1,3,5 (10)-trien-3-yl 2-substituted sulfamates | STERIX LIMITED (GB) | 2006-07-13 | — | — | US | claimed |
| CN-1751059-A | 2-substituted estra-1, 3,5(10) -trien-3-yl sulfamates having antitumor activity | SCHERING AG (DE) | 2006-03-22 | — | — | CN | claimed |
| CN-1751060-A | Antitumoral 18a-homoestra-1,3,5(10)-trien-3-yl 2-substituted sulfamates | SCHERING AG (DE) | 2006-03-22 | — | — | CN | claimed |
| CN-1751061-A | Antitumoral d-homoestra-1, 3, 5 (10)-trien-3-yl 2-substituted sulfamates | SCHERING AG (DE) | 2006-03-22 | — | — | CN | claimed |
| EP-1517914-B1 | 9-ALPHA-SUBSTITUTED ESTRATRIENES AS SELECTIVELY ACTIVE ESTROGEN | SCHERING AG (DE) | 2005-08-31 | — | — | EP | claimed |
| CN-1192021-C | 3-azabicyclo [3.1.0] hexane derivatives as opioid receptor ligands | PFIZER LTD (US) | 2005-03-09 | — | — | CN | claimed |
| US-6583130-B1 | Substituted with acyl, oxycarbonyl, aminocarbonyl, sulfonyl, or aminosulfonyl; inhibit steroid sulfatase, do not exhibit any estrogenic effect and will not yield any estrogenic products on hydrolysis; treatment of estrogen-dependent tumors | SCHERING AG (DE) | 2003-06-24 | — | — | US | claimed |
| EP-4739669-A1 | SODIUM CHANNEL BLOCKERS | Novartis AG (CH) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025011450-A1 | SODIUM CHANNEL BLOCKERS | NOVARTIS AG (CH) | 2025-01-16 | — | — | WO | disclosed |
| CN-118303677-A | Aerosol Generating System | 尼科创业贸易有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-113660876-B | Aerosol Generating System | 尼科创业贸易有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-1433396-A | Pharmaceutical compounds | NICOX SA (FR) | 2003-07-30 | — | — | CN | disclosed |
| US-6583130-B1 | Substituted with acyl, oxycarbonyl, aminocarbonyl, sulfonyl, or aminosulfonyl; inhibit steroid sulfatase, do not exhibit any estrogenic effect and will not yield any estrogenic products on hydrolysis; treatment of estrogen-dependent tumors | SCHERING AG (DE) | 2003-06-24 | — | — | US | disclosed |
| CN-1331679-A | 3-azabicyclo [3.1.0] hexane derivatives as opiate receptors ligands | PFIZER LTD (US) | 2002-01-16 | — | — | CN | disclosed |
| WO-1992002665-A1 | PROCESS FOR CLEANING AND DEGREASING, SPONTANEOUSLY EMULSIFYING PREMIX FOR USE AT THE PROCESS AND THE RESULTING EMULTION | ERIKSSON TORD GEORG (SE) | 1992-02-20 | — | — | WO | disclosed |