Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857643 | 0.89 | LMNA (0.48) | LMNANPSR1HPGDXBP1SMN1; SMN2 | |
| SCHEMBL2867187 | 0.87 | LMNA (0.44) | LMNANPSR1HPGDXBP1SMN1; SMN2 | |
| SCHEMBL2865122 | 0.85 | LMNA (0.43) | LMNANPSR1HPGDXBP1SMN1; SMN2 | |
| SCHEMBL2867590 | 0.85 | LMNA (0.43) | LMNANPSR1HPGDXBP1SMN1; SMN2 | |
| SCHEMBL2864128 | 0.85 | LMNA (0.43) | LMNANPSR1HPGDXBP1SMN1; SMN2 | |
| SCHEMBL2857817 | 0.79 | MAPT (0.35) | NPSR1MAPTTDP1 | |
| SCHEMBL2003079 | 0.78 | LMNA (0.32) | LMNANPSR1HPGDXBP1SMN1; SMN2 | |
| SCHEMBL25199269 | 0.76 | HTT (0.39) | HTT | |
| SCHEMBL7155142 | 0.72 | LMNA (0.33) | LMNANPSR1HPGDXBP1SMN1; SMN2 | |
| SCHEMBL7151811 | 0.72 | HTT (0.30) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247058-A1 | RESIN COMPOSITION FOR OPTICAL WAVEGUIDE AND OPTICAL WAVEGUIDE | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2010-09-30 | — | — | US | disclosed |
| EP-2211214-A1 | RESIN COMPOSITION FOR OPTICAL WAVEGUIDE AND OPTICAL WAVEGUIDE | Hitachi Chemical Company, Ltd. (JP) | 2010-07-28 | — | — | EP | disclosed |