Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | UBE2M | P61081 | 2/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.33 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14258156 | 0.87 | NR1H4 (0.45) | MAPTCCR1KEAP1NFE2L2NR1H4 | |
| SCHEMBL2860656 | 0.86 | MAPT (0.41) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL2852324 | 0.85 | MAPT (0.40) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL2855788 | 0.83 | MAPT (0.42) | MAPTMEN1KMT2ANPSR1KEAP1 | |
| SCHEMBL2856122 | 0.83 | MAPT (0.39) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL2852774 | 0.83 | BRAF (0.39) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL2859938 | 0.83 | MAPT (0.45) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL2855798 | 0.81 | MAPT (0.45) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL2848615 | 0.81 | MAPT (0.44) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL2850258 | 0.80 | MAPT (0.51) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |