Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 1/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL294699 | 0.93 | KDM1A (0.40) | CCNKCDK12EGLN1MEN1KMT2A | |
| SCHEMBL2722435 | 0.88 | KDM4A (0.42) | CCNKCDK12KDM4AKDM5CKDM4C | |
| SCHEMBL10325548 | 0.87 | NTRK1 (0.40) | CCNKCDK12KDM4AKDM5CKDM4C | |
| SCHEMBL718773 | 0.86 | CCNK (0.44) | CCNKCDK12KDM4AKDM5CKDM4C | |
| SCHEMBL299949 | 0.82 | KDR (0.47) | EGLN1CDC7GSK3BHDAC8 | |
| SCHEMBL719178 | 0.79 | KDM1A (0.45) | CCNKCDK12EGLN1MEN1KMT2A | |
| SCHEMBL27850091 | 0.78 | CCNK (0.49) | CCNKCDK12KDM4AKDM5CKDM4C | |
| SCHEMBL10325505 | 0.78 | EGLN1 (0.39) | CCNKCDK12KDM4AKDM5CKDM4C | |
| SCHEMBL10072164 | 0.75 | KDM4A (0.44) | CCNKCDK12KDM4AKDM5CKDM4C | |
| SCHEMBL10463930 | 0.73 | KDM4A (0.42) | CCNKCDK12KDM4AKDM5CKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427461-B1 | 3-([1,2,3]TRIAZOL-4-YL)-PYRROLO[2,3-B]PYRIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2013-10-09 | — | — | EP | disclosed |
| EP-2427461-A1 | 3-(Ý1,2,3¨TRIAZOLE-4-YL)-PYRROLOÝ2,3-B¨PYRIDINE DERIVATES | Merck Patent GmbH (DE) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010127754-A1 | 3-([1,2,3]TRIAZOLE-4-YL)-PYRROLO[2,3-B]PYRIDINE DERIVATES | MERCK PATENT GMBH (DE) | 2010-11-11 | — | — | WO | disclosed |