SCHEMBL28564200

SCHEMBL28564200

CCC(NC(=O)OC(C)(C)C)O[Si](C)(C)C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CTSK P43235 11/20 0.42
CTSS P25774 5/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CYP2D6 P10635 1/20 0.38
ALDH1A1 P00352 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
TSHR P16473 2/20 0.36
LMNA P02545 2/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9690240 0.84 CA1 (0.40) CTSKCTSSCA1CA2CA7
SCHEMBL592276 0.78 CA1 (0.35) CTSKCTSSCA1CA2CA7
SCHEMBL10650736 0.76 CTSK (0.46) CTSKCTSSCA1CA2CA7
SCHEMBL1722779 0.75 CTSK (0.36) CTSKCTSSCA1CA2CA7
SCHEMBL27567084 0.75 CTSK (0.45) CTSKCTSSCA1CA2CA7
SCHEMBL27567001 0.75 CTSK (0.45) CTSKCTSSCA1CA2CA7
SCHEMBL4973869 0.74 CA1 (0.41) CTSKCTSSCA1CA2CA7
SCHEMBL22526271 0.74 CA1 (0.49) CTSKCTSSCA1CA2CA7
SCHEMBL1863352 0.74 CA1 (0.45) CTSKCTSSCA1CA2CA7
SCHEMBL26205581 0.74 CA1 (0.49) CTSKCTSSCA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112920065-B Benzil compound and preparation method and application thereof 上海中医药大学 2023-04-25 CN disclosed
CN-112920065-A Benzil compound and preparation method and application thereof 上海中医药大学 2021-06-08 CN disclosed