Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218572 | 0.97 | CA12 (0.42) | DNM1CA12CA1CA9MAPT | |
| SCHEMBL219200 | 0.97 | CA12 (0.42) | DNM1CA12CA1CA9MAPT | |
| SCHEMBL3480441 | 0.97 | CA12 (0.42) | DNM1CA12CA1CA9MAPT | |
| Arsenic SCHEMBL15988577 | 0.93 | CA12 (0.40) | DNM1CA12CA1CA9MAPT | |
| Ammonia Solution, Strong SCHEMBL2783719 | 0.93 | CA12 (0.40) | DNM1CA12CA1CA9MAPT | |
| Hydrochloric Acid SCHEMBL11442180 | 0.93 | DNM1 (0.41) | DNM1CA12CA1CA9MAPT | |
| Fluoride SCHEMBL7561486 | 0.93 | CA12 (0.40) | DNM1CA12CA1CA9MAPT | |
| Hydrochloric Acid SCHEMBL8540929 | 0.93 | DNM1 (0.41) | DNM1CA12CA1CA9MAPT | |
| Ammonia Solution, Strong SCHEMBL27962616 | 0.93 | CA12 (0.40) | DNM1CA12CA1CA9MAPT | |
| SCHEMBL12994202 | 0.93 | CA12 (0.40) | DNM1CA12CA1CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112794829-A | Epoxy compound, composition, material for semiconductor encapsulation, molded product, electrical and electronic device, and semiconductor encapsulation | 三星电子株式会社 | 2021-05-14 | — | — | CN | disclosed |