SCHEMBL28564397

SCHEMBL28564397

Fc1ccn2ccccc12

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.40
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
KLK7 P49862 1/20 0.32
RHEB Q15382 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
CDK4 P11802 1/20 0.31
CCND1 P24385 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10149520 0.84 KDM4E (0.39) ALOX15KDM4EALDH1A1GAAHPGD
SCHEMBL31609391 0.74 ALOX15 (0.43) ALOX15NPC1RAB9AKDM4EALDH1A1
SCHEMBL5356722 0.70 ALOX15 (0.40) ALOX15RAB9AKDM4EALDH1A1GAA
SCHEMBL2005730 0.70 ALOX15 (0.40) ALOX15KDM4EALDH1A1GAAHPGD
SCHEMBL28372316 0.70 ALOX15 (0.40) ALOX15NPC1RAB9AKDM4EALDH1A1
SCHEMBL2005732 0.70 ALOX15 (0.40) ALOX15NPC1RAB9AKDM4EALDH1A1
SCHEMBL277729 0.70 ALOX15 (0.40) ALOX15NPC1RAB9AKDM4EALDH1A1
SCHEMBL16915952 0.70 ALOX15 (0.40) ALOX15NPC1RAB9AKDM4EALDH1A1
SCHEMBL4397520 0.70 KDM4E (0.41) ALOX15NPC1RAB9AKDM4EALDH1A1
SCHEMBL5356727 0.70 ALOX15 (0.40) ALOX15KDM4EALDH1A1GAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113563328-B Preparation method of 1, 3-disubstituted-2-fluoro indolizine derivative 台州学院 2022-07-05 CN disclosed
CN-114080155-A Shear stable compositions for spray drift control 巴斯夫欧洲公司 2022-02-22 CN disclosed
CN-114062551-A Method for detecting content of triflumizole amine and metabolites thereof on vegetables and fruits 上海市农业科学院 2022-02-18 CN disclosed
CN-113563328-A Preparation method of 1, 3-disubstituted-2-fluoro indolizine derivative 台州学院 2021-10-29 CN disclosed
CN-112888310-A Additive for stabilizing polyacrylamide copolymer solutions under high shear conditions 巴斯夫欧洲公司 2021-06-01 CN disclosed