Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 20/20 | 0.57 |
| ▸ | SCN1A | P35498 | 19/20 | 0.57 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL30845609 | 1.00 | SCN8A (0.57) | SCN8ASCN1ASCN5A | |
| Formic Acid SCHEMBL21773131 | 1.00 | SCN8A (0.57) | SCN8ASCN1ASCN5A | |
| Formic Acid SCHEMBL30845630 | 0.86 | SCN8A (0.59) | SCN8ASCN1A | |
| Formic Acid SCHEMBL21773163 | 0.86 | SCN8A (0.59) | SCN8ASCN1A | |
| Formic Acid SCHEMBL28571048 | 0.86 | SCN8A (0.59) | SCN8ASCN1A | |
| SCHEMBL21789096 | 0.81 | SCN8A (0.63) | SCN8ASCN1A | |
| SCHEMBL28535697 | 0.80 | SCN8A (0.62) | SCN8ASCN1ASCN5A | |
| Formic Acid SCHEMBL28549350 | 0.79 | SCN8A (0.92) | SCN8ASCN1A | |
| Formic Acid SCHEMBL21772995 | 0.79 | SCN8A (0.92) | SCN8ASCN1A | |
| SCHEMBL28532619 | 0.78 | SCN8A (0.63) | SCN8ASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638898-B | Heteroaryl substituted sulfonamide compounds and their use as sodium channel inhibitors | 泽农医药公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-112638898-A | Heteroaryl substituted sulfonamide compounds and their use as sodium channel inhibitors | 泽农医药公司 | 2021-04-09 | — | — | CN | disclosed |