Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27971160 | 0.98 | TAAR1 (0.48) | TAAR1KCNN4SLC6A2TACR1MAPK1 | |
| SCHEMBL155932 | 0.97 | TAAR1 (0.52) | TAAR1KCNN4SLC6A2TACR1MAPK1 | |
| SCHEMBL20169328 | 0.87 | MEN1 (0.42) | TAAR1KCNN4SLC6A2TACR1MAPT | |
| SCHEMBL28807710 | 0.81 | TAAR1 (0.46) | TAAR1KCNN4SLC6A2TACR1MAPK1 | |
| SCHEMBL1455824 | 0.80 | TAAR1 (0.50) | TAAR1KCNN4SLC6A2TACR1MAPK1 | |
| SCHEMBL18826628 | 0.80 | PDE2A (0.46) | TAAR1KCNN4SLC6A2TACR1MAPT | |
| SCHEMBL77069 | 0.80 | TAAR1 (0.62) | TAAR1KCNN4SLC6A2TACR1MAPK1 | |
| SCHEMBL19480335 | 0.80 | TSHR (0.46) | MAPK1MAPTKMT2AALDH1A1CYP1A2 | |
| SCHEMBL1456007 | 0.80 | TAAR1 (0.50) | TAAR1KCNN4SLC6A2TACR1MAPK1 | |
| SCHEMBL744277 | 0.80 | TAAR1 (0.50) | TAAR1KCNN4SLC6A2TACR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074823-B | Therapeutic compounds and uses thereof | 基因泰克公司 | 2021-05-04 | — | — | CN | disclosed |