SCHEMBL744277

SCHEMBL744277

CC(N)(CO)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.50
ESR1 P03372 2/20 0.48
ESR2 Q92731 2/20 0.48
ALDH1A1 P00352 2/20 0.48
CYP3A4 P08684 1/20 0.48
KCNN4 O15554 1/20 0.48
MAPT P10636 1/20 0.46
KMT2A Q03164 1/20 0.46
CYP2C19 P33261 1/20 0.45
HIF1A Q16665 1/20 0.45
ALOX15 P16050 1/20 0.44
SLC6A2 P23975 1/20 0.44
KDM4E B2RXH2 2/20 0.44
POLB P06746 1/20 0.44
TACR1 P25103 1/20 0.43
MAPK1 P28482 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
KIF11 P52732 1/20 0.39
HDAC3 O15379 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1455824 1.00 TAAR1 (0.50) TAAR1ESR1ESR2ALDH1A1CYP3A4
SCHEMBL1456007 1.00 TAAR1 (0.50) TAAR1ESR1ESR2ALDH1A1CYP3A4
Hydrochloric Acid SCHEMBL1455023 0.98 TAAR1 (0.48) TAAR1ESR1ESR2ALDH1A1CYP3A4
Hydrochloric Acid SCHEMBL1439423 0.98 TAAR1 (0.48) TAAR1ESR1ESR2ALDH1A1CYP3A4
SCHEMBL27798200 0.84 TAAR1 (0.45) TAAR1ESR1ESR2ALDH1A1CYP3A4
SCHEMBL1455173 0.84 TAAR1 (0.45) TAAR1ESR1ESR2ALDH1A1CYP3A4
SCHEMBL155932 0.82 TAAR1 (0.52) TAAR1ESR1ESR2ALDH1A1CYP3A4
SCHEMBL8891278 0.80 LMNA (0.56) ESR1ESR2ALDH1A1CYP3A4MAPT
Ammonia Solution, Strong SCHEMBL28564622 0.80 TAAR1 (0.50) TAAR1ESR1ESR2ALDH1A1CYP3A4
SCHEMBL7837799 0.80 ESR1 (0.56) ESR1ESR2ALDH1A1CYP3A4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3135109-B1 AMINOALCOHOL AND BIOCIDE COMPOSITIONS FOR AQUEOUS BASED SYSTEMS ANGUS CHEMICAL (US) 2020-02-12 EP claimed
EP-3135109-A1 AMINOALCOHOL AND BIOCIDE COMPOSITIONS FOR AQUEOUS BASED SYSTEMS ANGUS Chemical Company (US) 2017-03-01 EP claimed
EP-2282634-B1 AMINOALCOHOL AND BIOCIDE COMPOSITIONS FOR AQUEOUS BASED SYSTEMS ANGUS CHEMICAL (US) 2016-11-23 EP claimed
CN-102026542-B Aminoalcohol and biocide compositions for aqueous based systems ANGUS CHEMICAL 2014-08-20 CN claimed
US-8697754-B2 Aminoalcohol and biocide compositions for aqueous based systems DOW GLOBAL TECHNOLOGIES LLC 2014-04-15 US claimed
CN-102026541-A Improved corrosion and microbial control in hydrocarbonaceous compositions ANGUS CHEMICAL 2011-04-20 CN claimed
CN-102026542-A Aminoalcohol and biocide compositions for aqueous based systems ANGUS CHEMICAL 2011-04-20 CN claimed
EP-2299811-A1 IMPROVED CORROSION AND MICROBIAL CONTROL IN HYDROCARBONACEOUS COMPOSITIONS ANGUS CHEMICAL COMPANY (US) 2011-03-30 EP claimed
US-20110041387-A1 CORROSION AND MICROBIAL CONTROL IN HYDROCARBONACEOUS COMPOSITIONS ADVANCION CORPORATION 2011-02-24 US claimed
US-20110046140-A1 AMINOALCOHOL AND BIOCIDE COMPOSITIONS FOR AQUEOUS BASED SYSTEMS ADVANCION CORPORATION 2011-02-24 US claimed
EP-2282634-A2 AMINOALCOHOL AND BIOCIDE COMPOSITIONS FOR AQUEOUS BASED SYSTEMS ANGUS CHEMICAL COMPANY (US) 2011-02-16 EP claimed
WO-2009140062-A1 IMPROVED CORROSION AND MICROBIAL CONTROL IN HYDROCARBONACEOUS COMPOSITIONS ANGUS CHEMICAL COMPANY (US) 2009-11-19 WO claimed
WO-2009140061-A2 AMINOALCOHOL AND BIOCIDE COMPOSITIONS FOR AQUEOUS BASED SYSTEMS ANGUS CHEMICAL COMPANY (US) 2009-11-19 WO claimed
CN-114948963-B Benzolactam compounds as protein kinase inhibitors 大冢制药株式会社 2025-05-27 CN disclosed
EP-3247347-B1 ANTI-BACTERIAL COMPOSITIONS BIOCIDIUM IP HOLDCO CO (CA) 2025-01-08 EP disclosed
US-20240368136-A1 BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2024-11-07 US disclosed
US-4094911-A STABILITY AND SOLVENT RESISTANCE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-06-13 US disclosed
US-4085137-A FOR MAKING POLYURETHANES WITH LOW TEMPERATURE STABILITY AND SOLVENT RESISTANCE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-04-18 US disclosed
US-3972856-A LOW TEMPERATURE FLEXIBLE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-08-03 US disclosed
US-3969560-A Copolymers of monounsaturated or diunsaturated polyesters with vinyl monomers ROHM AND HAAS COMPANY (US) 1976-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240368136-A1 BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS MAPK1, ALK, MAP3K1 TAAR1 686/4885ESR1 1958/4885ESR2 2188/4885
US-20110046140-A1 AMINOALCOHOL AND BIOCIDE COMPOSITIONS FOR AQUEOUS BASED SYSTEMS ADH1C, ADH1A, ADH5 TAAR1 7/4885ESR1 1559/4885ESR2 3474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.