Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.48 |
| ▸ | PPARA | Q07869 | 15/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28564654 | 1.00 | PPARG (0.48) | PPARGPPARACYP2C9CYP2C19KDM4E | |
| SCHEMBL28558470 | 0.84 | PPARG (0.53) | PPARGPPARACYP2C9CYP2C19SLC6A4 | |
| SCHEMBL28558472 | 0.84 | PPARG (0.53) | PPARGPPARACYP2C9CYP2C19SLC6A4 | |
| SCHEMBL28549050 | 0.81 | PPARG (0.50) | PPARGPPARASLC6A4 | |
| SCHEMBL28549052 | 0.81 | PPARG (0.50) | PPARGPPARASLC6A4 | |
| SCHEMBL28700053 | 0.74 | PPARG (0.43) | PPARGPPARAALDH1A1SLC6A4 | |
| SCHEMBL28700052 | 0.74 | PPARG (0.43) | PPARGPPARAALDH1A1SLC6A4 | |
| SCHEMBL9660791 | 0.74 | SLC6A2 (0.52) | PPARGPPARACYP2C9CYP2C19KDM4E | |
| SCHEMBL21978785 | 0.73 | PPARG (0.48) | PPARGPPARA | |
| SCHEMBL11304092 | 0.71 | PPARA (0.53) | PPARGPPARASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107848962-B | Urea derivative or pharmacologically acceptable salt thereof | 杏林制药株式会社 | 2021-04-09 | — | — | CN | disclosed |