SCHEMBL28558472

SCHEMBL28558472

NC(=O)OC(Cc1ccc(Cl)cc1)C(N)=O

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PPARG P37231 15/20 0.53
PPARA Q07869 15/20 0.53
SLC6A4 P31645 1/20 0.46
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A3 Q01959 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28558470 1.00 PPARG (0.53) PPARGPPARASLC6A4CYP2C9CYP2C19
SCHEMBL28549050 0.87 PPARG (0.50) PPARGPPARASLC6A4
SCHEMBL28549052 0.87 PPARG (0.50) PPARGPPARASLC6A4
SCHEMBL28564654 0.84 PPARG (0.48) PPARGPPARASLC6A4CYP2C9CYP2C19
SCHEMBL28564655 0.84 PPARG (0.48) PPARGPPARASLC6A4CYP2C9CYP2C19
SCHEMBL11304092 0.83 PPARA (0.53) PPARGPPARASLC6A4SLC6A2SLC6A3
SCHEMBL28982634 0.82 SRR (0.58) PPARGPPARA
SCHEMBL28549393 0.80 LDHA (0.56) PPARGPPARASLC6A4CYP2C19
SCHEMBL29073302 0.80 SRR (0.62) PPARGPPARA
SCHEMBL28700053 0.79 PPARG (0.43) PPARGPPARASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107848962-B Urea derivative or pharmacologically acceptable salt thereof 杏林制药株式会社 2021-04-09 CN disclosed