Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20722765 | 1.00 | BACE1 (0.47) | BACE1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL20722760 | 0.90 | CA1 (0.42) | L3MBTL1ACHECA1CA2ALDH1A1 | |
| SCHEMBL21686008 | 0.90 | CA1 (0.42) | L3MBTL1ACHECA1CA2ALDH1A1 | |
| SCHEMBL21686007 | 0.90 | CA1 (0.42) | L3MBTL1ACHECA1CA2ALDH1A1 | |
| SCHEMBL30968513 | 0.89 | BACE1 (0.46) | BACE1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL20722887 | 0.89 | BACE1 (0.46) | BACE1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL29286138 | 0.89 | BACE1 (0.46) | BACE1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL21685901 | 0.88 | CA1 (0.45) | BACE1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL21685906 | 0.88 | RORC (0.40) | BACE1MAPTKMT2AMAPK1NPSR1 | |
| SCHEMBL20722698 | 0.85 | BACE1 (0.45) | BACE1MAPTMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-112867712-A | Carboxamides as ubiquitin-specific protease inhibitors | 瓦洛早期发现股份有限公司 | 2021-05-28 | — | — | CN | disclosed |